PKA-dependent regulation of Cdc25 RasGEF localization in budding yeast
نویسندگان
چکیده
منابع مشابه
Model-guided optogenetic study of PKA signaling in budding yeast
In eukaryotes, protein kinase A (PKA) is a master regulator of cell proliferation and survival. The activity of PKA is subject to elaborate control and exhibits complex time dynamics. To probe the quantitative attributes of PKA dynamics in the yeast Saccharomyces cerevisiae, we developed an optogenetic strategy that uses a photoactivatable adenylate cyclase to achieve real-time regulation of cA...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 2011
ISSN: 0014-5793
DOI: 10.1016/j.febslet.2011.10.032